Model info
| Transcription factor | NR1H3 (GeneCards) | ||||||||
| Model | NR1H3_HUMAN.H11MO.1.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 10 | ||||||||
| Quality | B | ||||||||
| Motif rank | 1 | ||||||||
| Consensus | hvAGGKCAvd | ||||||||
| Best auROC (human) | 0.761 | ||||||||
| Best auROC (mouse) | 0.903 | ||||||||
| Peak sets in benchmark (human) | 13 | ||||||||
| Peak sets in benchmark (mouse) | 10 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | Thyroid hormone receptor-related factors (NR1) {2.1.2} | ||||||||
| TF subfamily | LXR (NR1H) {2.1.2.7} | ||||||||
| HGNC | HGNC:7966 | ||||||||
| EntrezGene | GeneID:10062 (SSTAR profile) | ||||||||
| UniProt ID | NR1H3_HUMAN | ||||||||
| UniProt AC | Q13133 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | NR1H3 expression | ||||||||
| ReMap ChIP-seq dataset list | NR1H3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 244.0 | 139.0 | 50.0 | 67.0 |
| 02 | 228.0 | 133.0 | 124.0 | 15.0 |
| 03 | 439.0 | 3.0 | 48.0 | 10.0 |
| 04 | 6.0 | 0.0 | 488.0 | 6.0 |
| 05 | 3.0 | 4.0 | 442.0 | 51.0 |
| 06 | 53.0 | 63.0 | 77.0 | 307.0 |
| 07 | 3.0 | 485.0 | 7.0 | 5.0 |
| 08 | 491.0 | 4.0 | 4.0 | 1.0 |
| 09 | 103.0 | 162.0 | 175.0 | 60.0 |
| 10 | 205.0 | 74.0 | 137.0 | 84.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.663 | 0.105 | -0.898 | -0.613 |
| 02 | 0.595 | 0.061 | -0.008 | -2.034 |
| 03 | 1.247 | -3.325 | -0.938 | -2.394 |
| 04 | -2.819 | -4.4 | 1.353 | -2.819 |
| 05 | -3.325 | -3.126 | 1.254 | -0.879 |
| 06 | -0.841 | -0.673 | -0.477 | 0.891 |
| 07 | -3.325 | 1.347 | -2.694 | -2.961 |
| 08 | 1.359 | -3.126 | -3.126 | -3.903 |
| 09 | -0.191 | 0.256 | 0.333 | -0.721 |
| 10 | 0.49 | -0.516 | 0.091 | -0.392 |