Model info
| Transcription factor | ESR1 (GeneCards) | ||||||||
| Model | ESR1_HUMAN.H11MO.1.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 10 | ||||||||
| Quality | A | ||||||||
| Motif rank | 1 | ||||||||
| Consensus | hhRGGTCAbv | ||||||||
| Best auROC (human) | 0.935 | ||||||||
| Best auROC (mouse) | 0.957 | ||||||||
| Peak sets in benchmark (human) | 432 | ||||||||
| Peak sets in benchmark (mouse) | 58 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | Steroid hormone receptors (NR3) {2.1.1} | ||||||||
| TF subfamily | ER-like receptors (NR3A&B) {2.1.1.2} | ||||||||
| HGNC | HGNC:3467 | ||||||||
| EntrezGene | GeneID:2099 (SSTAR profile) | ||||||||
| UniProt ID | ESR1_HUMAN | ||||||||
| UniProt AC | P03372 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | ESR1 expression | ||||||||
| ReMap ChIP-seq dataset list | ESR1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 61.0 | 273.0 | 60.0 | 106.0 |
| 02 | 175.0 | 163.0 | 59.0 | 103.0 |
| 03 | 316.0 | 8.0 | 174.0 | 2.0 |
| 04 | 3.0 | 0.0 | 483.0 | 14.0 |
| 05 | 3.0 | 0.0 | 496.0 | 1.0 |
| 06 | 19.0 | 2.0 | 51.0 | 428.0 |
| 07 | 2.0 | 487.0 | 10.0 | 1.0 |
| 08 | 497.0 | 1.0 | 2.0 | 0.0 |
| 09 | 34.0 | 222.0 | 185.0 | 59.0 |
| 10 | 159.0 | 168.0 | 123.0 | 50.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.705 | 0.774 | -0.721 | -0.163 |
| 02 | 0.333 | 0.263 | -0.737 | -0.191 |
| 03 | 0.92 | -2.584 | 0.327 | -3.573 |
| 04 | -3.325 | -4.4 | 1.343 | -2.096 |
| 05 | -3.325 | -4.4 | 1.369 | -3.903 |
| 06 | -1.818 | -3.573 | -0.879 | 1.222 |
| 07 | -3.573 | 1.351 | -2.394 | -3.903 |
| 08 | 1.371 | -3.903 | -3.573 | -4.4 |
| 09 | -1.27 | 0.569 | 0.388 | -0.737 |
| 10 | 0.238 | 0.293 | -0.016 | -0.898 |