Model info
| Transcription factor | IRF8 (GeneCards) | ||||||||
| Model | IRF8_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 20 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vdddvRGGAASTGAAASYdv | ||||||||
| Best auROC (human) | |||||||||
| Best auROC (mouse) | 0.996 | ||||||||
| Peak sets in benchmark (human) | |||||||||
| Peak sets in benchmark (mouse) | 59 | ||||||||
| Aligned words | 505 | ||||||||
| TF family | Interferon-regulatory factors {3.5.3} | ||||||||
| TF subfamily | IRF-8 (ICSBP1) {3.5.3.0.8} | ||||||||
| HGNC | HGNC:5358 | ||||||||
| EntrezGene | GeneID:3394 (SSTAR profile) | ||||||||
| UniProt ID | IRF8_HUMAN | ||||||||
| UniProt AC | Q02556 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | IRF8 expression | ||||||||
| ReMap ChIP-seq dataset list | IRF8 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 180.0 | 87.0 | 155.0 | 78.0 |
| 02 | 244.0 | 47.0 | 104.0 | 105.0 |
| 03 | 284.0 | 51.0 | 69.0 | 96.0 |
| 04 | 272.0 | 28.0 | 77.0 | 123.0 |
| 05 | 159.0 | 68.0 | 239.0 | 34.0 |
| 06 | 242.0 | 68.0 | 174.0 | 16.0 |
| 07 | 103.0 | 1.0 | 394.0 | 2.0 |
| 08 | 69.0 | 1.0 | 429.0 | 1.0 |
| 09 | 496.0 | 3.0 | 1.0 | 0.0 |
| 10 | 481.0 | 8.0 | 3.0 | 8.0 |
| 11 | 69.0 | 159.0 | 261.0 | 11.0 |
| 12 | 36.0 | 33.0 | 0.0 | 431.0 |
| 13 | 9.0 | 3.0 | 483.0 | 5.0 |
| 14 | 434.0 | 4.0 | 53.0 | 9.0 |
| 15 | 424.0 | 8.0 | 61.0 | 7.0 |
| 16 | 474.0 | 8.0 | 7.0 | 11.0 |
| 17 | 53.0 | 207.0 | 233.0 | 7.0 |
| 18 | 66.0 | 123.0 | 29.0 | 282.0 |
| 19 | 173.0 | 76.0 | 162.0 | 89.0 |
| 20 | 190.0 | 85.0 | 150.0 | 75.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.361 | -0.357 | 0.213 | -0.464 |
| 02 | 0.663 | -0.958 | -0.181 | -0.172 |
| 03 | 0.814 | -0.879 | -0.584 | -0.26 |
| 04 | 0.771 | -1.454 | -0.477 | -0.016 |
| 05 | 0.238 | -0.599 | 0.642 | -1.27 |
| 06 | 0.655 | -0.599 | 0.327 | -1.975 |
| 07 | -0.191 | -3.903 | 1.14 | -3.573 |
| 08 | -0.584 | -3.903 | 1.224 | -3.903 |
| 09 | 1.369 | -3.325 | -3.903 | -4.4 |
| 10 | 1.338 | -2.584 | -3.325 | -2.584 |
| 11 | -0.584 | 0.238 | 0.73 | -2.311 |
| 12 | -1.215 | -1.298 | -4.4 | 1.229 |
| 13 | -2.484 | -3.325 | 1.343 | -2.961 |
| 14 | 1.236 | -3.126 | -0.841 | -2.484 |
| 15 | 1.213 | -2.584 | -0.705 | -2.694 |
| 16 | 1.324 | -2.584 | -2.694 | -2.311 |
| 17 | -0.841 | 0.5 | 0.617 | -2.694 |
| 18 | -0.628 | -0.016 | -1.421 | 0.807 |
| 19 | 0.322 | -0.49 | 0.256 | -0.335 |
| 20 | 0.415 | -0.38 | 0.18 | -0.503 |