Model info
| Transcription factor | ISL1 (GeneCards) | ||||||||
| Model | ISL1_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 9 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vYWRAKKRv | ||||||||
| Best auROC (human) | 0.805 | ||||||||
| Best auROC (mouse) | 0.858 | ||||||||
| Peak sets in benchmark (human) | 3 | ||||||||
| Peak sets in benchmark (mouse) | 13 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | HD-LIM factors {3.1.5} | ||||||||
| TF subfamily | ISL {3.1.5.1} | ||||||||
| HGNC | HGNC:6132 | ||||||||
| EntrezGene | GeneID:3670 (SSTAR profile) | ||||||||
| UniProt ID | ISL1_HUMAN | ||||||||
| UniProt AC | P61371 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | ISL1 expression | ||||||||
| ReMap ChIP-seq dataset list | ISL1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 92.0 | 154.0 | 182.0 | 72.0 |
| 02 | 23.0 | 329.0 | 24.0 | 124.0 |
| 03 | 143.0 | 28.0 | 6.0 | 323.0 |
| 04 | 356.0 | 29.0 | 112.0 | 3.0 |
| 05 | 489.0 | 6.0 | 5.0 | 0.0 |
| 06 | 8.0 | 3.0 | 155.0 | 334.0 |
| 07 | 25.0 | 0.0 | 310.0 | 165.0 |
| 08 | 82.0 | 20.0 | 382.0 | 16.0 |
| 09 | 170.0 | 147.0 | 148.0 | 35.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.302 | 0.206 | 0.372 | -0.543 |
| 02 | -1.64 | 0.96 | -1.6 | -0.008 |
| 03 | 0.133 | -1.454 | -2.819 | 0.942 |
| 04 | 1.039 | -1.421 | -0.108 | -3.325 |
| 05 | 1.355 | -2.819 | -2.961 | -4.4 |
| 06 | -2.584 | -3.325 | 0.213 | 0.975 |
| 07 | -1.561 | -4.4 | 0.901 | 0.275 |
| 08 | -0.415 | -1.77 | 1.109 | -1.975 |
| 09 | 0.304 | 0.16 | 0.167 | -1.242 |