Model info
| Transcription factor | NR1H3 (GeneCards) | ||||||||
| Model | NR1H3_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 19 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vhvRGKYhAbhnnRGKdYA | ||||||||
| Best auROC (human) | 0.77 | ||||||||
| Best auROC (mouse) | 0.86 | ||||||||
| Peak sets in benchmark (human) | 13 | ||||||||
| Peak sets in benchmark (mouse) | 10 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | Thyroid hormone receptor-related factors (NR1) {2.1.2} | ||||||||
| TF subfamily | LXR (NR1H) {2.1.2.7} | ||||||||
| HGNC | HGNC:7966 | ||||||||
| EntrezGene | GeneID:10062 (SSTAR profile) | ||||||||
| UniProt ID | NR1H3_HUMAN | ||||||||
| UniProt AC | Q13133 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | NR1H3 expression | ||||||||
| ReMap ChIP-seq dataset list | NR1H3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 84.0 | 241.0 | 104.0 | 71.0 |
| 02 | 212.0 | 112.0 | 62.0 | 114.0 |
| 03 | 187.0 | 63.0 | 210.0 | 40.0 |
| 04 | 272.0 | 13.0 | 190.0 | 25.0 |
| 05 | 61.0 | 3.0 | 407.0 | 29.0 |
| 06 | 19.0 | 22.0 | 378.0 | 81.0 |
| 07 | 32.0 | 79.0 | 76.0 | 313.0 |
| 08 | 72.0 | 214.0 | 42.0 | 172.0 |
| 09 | 415.0 | 9.0 | 27.0 | 49.0 |
| 10 | 57.0 | 296.0 | 71.0 | 76.0 |
| 11 | 112.0 | 89.0 | 43.0 | 256.0 |
| 12 | 120.0 | 114.0 | 145.0 | 121.0 |
| 13 | 114.0 | 162.0 | 142.0 | 82.0 |
| 14 | 330.0 | 45.0 | 86.0 | 39.0 |
| 15 | 40.0 | 13.0 | 418.0 | 29.0 |
| 16 | 53.0 | 20.0 | 359.0 | 68.0 |
| 17 | 76.0 | 69.0 | 110.0 | 245.0 |
| 18 | 39.0 | 369.0 | 36.0 | 56.0 |
| 19 | 436.0 | 22.0 | 24.0 | 18.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.392 | 0.651 | -0.181 | -0.556 |
| 02 | 0.523 | -0.108 | -0.689 | -0.091 |
| 03 | 0.399 | -0.673 | 0.514 | -1.114 |
| 04 | 0.771 | -2.163 | 0.415 | -1.561 |
| 05 | -0.705 | -3.325 | 1.172 | -1.421 |
| 06 | -1.818 | -1.681 | 1.098 | -0.427 |
| 07 | -1.328 | -0.452 | -0.49 | 0.91 |
| 08 | -0.543 | 0.533 | -1.067 | 0.316 |
| 09 | 1.191 | -2.484 | -1.489 | -0.918 |
| 10 | -0.771 | 0.855 | -0.556 | -0.49 |
| 11 | -0.108 | -0.335 | -1.044 | 0.711 |
| 12 | -0.04 | -0.091 | 0.147 | -0.032 |
| 13 | -0.091 | 0.256 | 0.126 | -0.415 |
| 14 | 0.963 | -1.0 | -0.368 | -1.138 |
| 15 | -1.114 | -2.163 | 1.199 | -1.421 |
| 16 | -0.841 | -1.77 | 1.047 | -0.599 |
| 17 | -0.49 | -0.584 | -0.126 | 0.667 |
| 18 | -1.138 | 1.074 | -1.215 | -0.788 |
| 19 | 1.241 | -1.681 | -1.6 | -1.868 |