Model info
Transcription factorIRF8
(GeneCards)
ModelIRF8_HUMAN.H11MO.0.B
Model typeMononucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length20
Quality
B
Motif rank
0
ConsensusvdddvRGGAASTGAAASYdv
Best auROC (human)
Best auROC (mouse)0.996
Peak sets in benchmark (human)
Peak sets in benchmark (mouse)59
Aligned words505
TF familyInterferon-regulatory factors {3.5.3}
TF subfamilyIRF-8 (ICSBP1) {3.5.3.0.8}
HGNCHGNC:5358
EntrezGeneGeneID:3394
(SSTAR profile)
UniProt IDIRF8_HUMAN
UniProt ACQ02556
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 3.7850099999999998
0.0005 5.03496
0.0001 7.63016
GTEx tissue expression atlas IRF8 expression
ReMap ChIP-seq dataset list IRF8 datasets
Motifs in JASPAR
PCM
ACGT
01180.087.0155.078.0
02244.047.0104.0105.0
03284.051.069.096.0
04272.028.077.0123.0
05159.068.0239.034.0
06242.068.0174.016.0
07103.01.0394.02.0
0869.01.0429.01.0
09496.03.01.00.0
10481.08.03.08.0
1169.0159.0261.011.0
1236.033.00.0431.0
139.03.0483.05.0
14434.04.053.09.0
15424.08.061.07.0
16474.08.07.011.0
1753.0207.0233.07.0
1866.0123.029.0282.0
19173.076.0162.089.0
20190.085.0150.075.0
PWM
ACGT
010.361-0.3570.213-0.464
020.663-0.958-0.181-0.172
030.814-0.879-0.584-0.26
040.771-1.454-0.477-0.016
050.238-0.5990.642-1.27
060.655-0.5990.327-1.975
07-0.191-3.9031.14-3.573
08-0.584-3.9031.224-3.903
091.369-3.325-3.903-4.4
101.338-2.584-3.325-2.584
11-0.5840.2380.73-2.311
12-1.215-1.298-4.41.229
13-2.484-3.3251.343-2.961
141.236-3.126-0.841-2.484
151.213-2.584-0.705-2.694
161.324-2.584-2.694-2.311
17-0.8410.50.617-2.694
18-0.628-0.016-1.4210.807
190.322-0.490.256-0.335
200.415-0.380.18-0.503